Gene Therapy Solutions

Gene Silencing

Gene silencing is a technique with which geneticists can deactivate an existing gene. By turning off defective genes, the harmful effects of that gene can be prevented.

This is accomplished by binding a specific strand of RNA to an existing mRNA (messenger RNA) strand. Ordinarily, when DNA replicates, the mRNA creates a copy of the DNA strand. But by binding the RNA to the mRNA, the mRNA is prevented from replicating that portion of the DNA. Therefore, specific genes can be targeted and prevented from replicating into new DNA strands.

Viruses like Hepatitis and AIDS can be treated using gene silencing techniques.

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