Newborn screening and diagnostic model
The first and only in Vietnam
Newborn screening is the easiest method of detecting congenital abnormalities before they cause permanent damage
Worldwide
8
million babies
Are born with congenital abnormalities(*)
(*) According to the WHO
In vietnam
Every 13 minutes
a baby is born
with congenital abnormalities/year
41,000
children
with congenital abnormalities/year
On average
1 in 50
babies
With a G6PD deficiency
(**) Data from the Ministry of Health and Population Statistics 2017
What is the babySure test?
The babySure test is the first and only test model that combines biochemical screening with biochemical and genetic diagnosis for newborns in Vietnam. By combining fluorescent enzyme immunoassays and gene sequencing technology for genetic diagnostics, we can detect five congenital metabolic disorders in children, thereby providing effective treatment and timely intervention. If the newborn screening result is positive, the diagnosis is the conclusive statement regarding a child's medical condition.
Benefits of babySure
- Early detection of endocrine and metabolic genetic disorders for newborns.
- Timely diagnosis and treatment, reducing the risk of complications and irreversible sequela.
- Reduce neonatal mortality and burden on family and society.
5 common endocrine and metabolic genetic disorders for newborns
G6PD Deficiency
G6PD deficiency causes hemolytic anaemia, neonatal jaundice and can cause irreversible brain damage.
Milk allergy (Galactose metabolism disorder)
Infants who are intolerant to galactose in milk can suffer from cataracts, retardation of psychomotor development and possibly death if not treated promptly.
Protein intolerance (Phenylketonuria)
The disease results in a deficiency of the enzyme that helps metabolise phenylalanine. If not treated in time, it will cause irreversible brain damage, a small head, and intellectual disability.
Congenital hypothyroidism
Diseases causing thyroid disorders have symptoms that include myxedema, jaundice and growth retardation. If not detected early and treated promptly, it will cause retardation of psychomotor development and dullness in children.
Congenital adrenal hyperplasia
Salt loss: hyponatremia, hyperkalemia, dehydration, lower blood pressure, slow weight gain, lower blood sugar.
Virilization: manifestations of virilization in girls: clitoris enlargement, labial fusion. In boys, early puberty.
Perfect time to perform babySure test
24 - 72 hours after birth
(48 hours postpartum is the golden hour)
- Collecting blood samples too early (before 24 hours) can easily lead to false positive results.
- Collecting blood samples too late (after 72 hours) doesn't affect the result-however, it will not ensure the objective of early detection and timely treatment.
Screening to diagnostic procedure
Frequently Asked Questions (FAQs)
1. Why is the time between 48 and 72 hours postpartum the golden time for performing babySure?
2. Why take a blood sample from the heel instead of another location?
3. How to get blood from a child's heel? Is there any danger to the child?
4. What are the clinical manifestations of these five diseases?
