Making cell-free DNA testing accessible to all healthcare providers
Screening solutions for the risk of the most prevalent hereditary cancers

Screening solutions for the risk of the most prevalent hereditary cancers

(Only one test. Results returned in 14 days)
Screening solutions for the risk of the most prevalent hereditary cancers
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Over

0.0

million new cases of cancer have been diagnosed (2020)

0.0

million deaths due to cancer (2020)

Over

0

Vietnamese people die from cancer every day

Every

0

people 1

person carries a cancer-causing gene (*)

  • Source: Global Cancer Statistics 2020
  • (*) Source: Data according to research by the Medical Genetics Institute — Gene Solutions
Genetics
Lifestyle
Environment

Major etiologies of cancer

The development of cancer in individuals results from the interaction of three factors:
  • Genetics (genes)
  • Lifestyle (diet, exercise, etc.)
  • Environment (air and water quality, stress in life)

The oncoSureTM genetic cancer screening test supports the analysis of cancer-related genetic components.

Learn more about the cancer detection, monitoring, and treatment tests offered by Gene Solutions.

Why should you take the oncoSure hereditary cancer screening test?

Advantages of oncoSure test

The results of the test allow for early detection of hereditary cancer risk:

  • Active cancer prevention includes medication treatment, and preventive surgery to reduce cancer risk.
  • Active screening helps early disease diagnosis, significantly improving cancer treatment outcomes.

Why should you take the oncoSure hereditary cancer screening test?

  • Analyzing and determining the cause of hereditary cancer in the family.
Support consultations with geneticists and oncologists and free testing for three close relatives.

(*) Source: Statistics adapted from the American Cancer Society's publication, Cancer Facts & Figures 2020, the ACS website, and the National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) Program (all sources accessed January 2020)

Scope of the test

  • OncoSure analyzes 17 genes (BRCA1, BRCA2, PALB2, PTEN, TP53, CDH1, MLH1, MSH2, MSH6, PMS2, EPCAM, APC, MUTYH, STK11, VHL, RB1, RET) associated with 15 common hereditary cancers (Skin Cancer, Ovarian Cancer, Neural paraganglioma, Colorectal Cancer, Stomach Cancer, Thyroid Cancer, Breast Cancer, Kidney Cancer, Multiple Endocrine Neoplasias, Lung Cancer, Endometrial Cancer, Adrenal Myeloma, Pancreatic Cancer, Prostate Cancer, Retinoblastoma).
  • oncoSure Plus is a package of screening tests for 133 genes associated with 30 common hereditary cancers.

Genetic mutations associated with hereditary cancer

NoHereditary cancerTesting genes
01Skin CancerBAP1, BRAF, BRCA2, CBL, CDK4, CDKN2A, CYLD, DDB2, DKC1, ERCC2, ERCC3, ERCC4, ERCC5, FH, FLCN, HNF1A, KITLG, MAP2K1, MAP2K2, MITF, NRAS, POLH, PTCH1, PTEN, RECQL4, TINF2, TP53, WRN, XPA, XPC
02Acute Leukemia (blood cancer)ANKRD26, BUB1B, CBL, CEBPA, CEP57, EGFR, ELANE, ETV6, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, FANCM, GATA2, NRAS, PAX5, PDGFRA, PRF1, PTPN11, RUNX1, SPRED1, SRP72, WT1
03Colorectal CancerAPC, AXIN2, BLM, BMPR1A, CBL, CDH1, CHEK2, DKC1, EPCAM, EXO1, GREM1, MLH1, MLH3, MSH2, MSH6, MUTYH, NRAS, NTHL1, PMS1, PMS2, POLD1, PTEN, SMAD4, SOS1, STK11, TP53
04Breast CancerATM, BARD1, BLM, BRCA1, BRCA2, CDH1, CHEK2, DKC1, MRE11A, NBN, NF1, PALB2, PMS1, PPM1D, PTEN, RAD50, SHOC2, SLX4, STK11, TP53, XRCC2
05Lung CancerBRAF, DICER1, DKC1, EGFR, ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, FLCN, KRAS, MAP2K1, MAP2K2, NRAS, RET, SMARCA4, SOS1, TERC, TERT
06Kidney CancerBAP1, BUB1B, CDKN1C, CEP57, DICER1, DIS3L2, EPCAM, FH, HNF1A, MET, MLH1, MSH2, MSH6, PMS2, SDHB, VHL, WT1
07Pancreatic CancerAPC, BMPR1A, BRCA1, BRCA2, CDK4, CDKN2A, DKC1, EPCAM, MLH1, MSH2, MSH6, PALB2, PMS2, SMAD4, STK11, TP53
08Ovarian CancerBRCA1, BRCA2, BRIP1, DICER1, EPCAM, ERCC1, MLH1, MRE11A, MSH2, MSH6, MUTYH, PALB2, PMS2, RAD51C, STK11, TP53
09Stomach CancerAPC, BMPR1A, CDH1, EPCAM, KIT, MLH1, MSH2, MSH6, NSUN2, PMS2, PTEN, SMAD4, STK11, TP53
10Bladder CancerATM, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, FANCM, HRAS, RAF1
11Endometrial CancerCBL, CDKN1C, EPCAM, FH, MLH1, MLH3, MSH2, MSH6, PMS2, PTEN, STK11, TP53
12Prostate CancerBRCA1, BRCA2, EPCAM, EZH2, HOXB13, MLH1, MSH2, MSH6, PALB2, PMS2, TP53
13Head and Neck CancerFANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, FANCM
14Brain CancerERCC2, ERCC3, ERCC4, ERCC5, NF1, NSD1, PHOX2B, SUFU
15Neural ParagangliomaRET, SDHA, SDHAF2, SDHB, SDHC, SDHD, VHL
16Biliary Tract CancerBAP1, BRAF, KRAS, NRAS, TSC1, TSC2
17Thyroid CancerCDKN1C, DICER1, RET, TINF2, WRN
18Bone CancerEXT1, EXT2, RECQL4, SMARCB1
19Multiple Endocrine NeoplasiasCDKN1B, MEN1, PRKAR1A, RET
20SarcomaBUB1B, CEP57, HRAS
21Liver CancerGPC3, HNF1A
22Small Bowel CancerBMPR1A, KIT
23Pituitary TumorAIP, DKC1
24NeuroblastomaALK, HRAS
25Nerve FibromaNF1, NF2
26Adrenal MyelomaMAX, RET, TMEM127
27Parathyroid CancerCDC73
28RetinoblastomaRB1
29Esophageal CancerRHBDF2
30Multiple MyelomaBRAF

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Testing candidates

Testing candidates

PERSONAL HISTORY

  • You or a loved one* has a rare form of cancer (for example, ovarian cancer, pancreatic cancer, male breast cancer, metastatic prostate cancer, triple-negative breast cancer, medullary thyroid).
  • You or a loved one has been diagnosed with cancer earlier than usual (For example, colorectal cancer, endometrial cancer, or breast cancer diagnosed before age 50).
  • You or a loved one has numerous types of cancer simultaneously, and cancer may present in two different organs (for example, bilateral breast cancer or kidney cancer).
  • A colonoscopy revealed more than ten colorectal polyps.
  • Being of a race or ethnicity with a hereditary predisposition for cancer (Example: Ashkenazi Jew).

FAMILY HISTORY

  • First-degree relatives (parent, sibling, or child) with cancer of the same type (Example: mother, daughter, and sister with breast cancer, etc.).
  • Relatives on the same side (mother or father) have the same cancer or related cancers (for example, breast, ovarian, pancreatic, prostate or colorectal cancer, endometrial cancer, uterus, stomach, ovaries, pancreas).
  • A family member has a genetic mutation that increases the risk of cancer.

CONCERNED ABOUT THE POSSIBILITY OF HEREDITARY CANCER INHERITANCE

  • Relatives include siblings, children, father, mother, uncle, aunt, grandfather, and grandmother.

(*) Source: National Institutes of Health.

What do you get from the test package?

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17 - 133 genes associated with 15 - 30 hereditary cancers are analyzed

Detects mutations in family-inherited genes that increase the risk of common types of cancer. The test results help you evaluate the probability that you will have certain cancers for yourself and your family

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Genetic counseling from geneticists

The team of experts and geneticists at Gene Solutions are always available to accompany you before and after each test and provide recommendations based on the results

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Modify the treatment plan

The results assist in tracking cancer/chronic disease progression and planning effective interventions. In addition, it is possible to improve the efficacy of treatment by choosing an appropriate regimen

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Guaranteed quality in every result

Next-generation sequencing technology (Illumina) from the United States was developed by Vietnam's leading medical advisors and a team of professionals. In only 14 days, a high-quality lab that complies with ISO standards will provide you with more than 99-percent-correct test results

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Simple to do and cost-effective

The USA standard DNA sampling kit, which allows you to collect samples at home in less than a minute, is painless and incredibly convenient

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Free testing for family members

If the initial test identifies a mutation, three family members will receive free testing. Take the initiative to prevent and protect your family's health

Testing process

Pre-test counselling
Pre-test counselling
Blood collection and extracellular DNA separation
Blood collection and extracellular DNA separation
Sequencing of cell-free DNA
Sequencing of cell-free DNA
Returning results and post-test counselling
Returning results and post-test counselling
CTA Form - Gene Solutions

Genetic consultation with our doctors

Besides you and your family before and after the test.