Latest Study In Genetics Of Miscarriage At Asia-Pacific Congress In Maternal Fetal Medicine (APCMFM 2024)

We are proud to announce that Dr. Nguyen Vu Khanh and Dr. Nguyen Son Tung from Gene Solutions attended and presented important findings in the genetics of miscarriage at the 17th APCMFM 2024. 

The study examined fetal or placental samples from miscarriages occurring under 24 weeks of gestation. Its purpose was to investigate the causes of early miscarriages by identifying abnormal copy number variations (CNVs) and single-gene mutations in miscarriage fetuses. To achieve this, the researchers utilized Next-Generation Sequencing (NGS) to analyze DNA libraries and detect genetic abnormalities, focusing on 4503 genes through Clinical Exome Sequencing (CES).

In 636 pregnancy loss cases, the study identified 223 cases with genetic abnormalities (96% chromosomal abnormalities and 4% single-gene variants). Chromosomal abnormalities are common genetic factors causing miscarriage. Identifying new genetic variations through this research may provide valuable insights into the molecular mechanisms leading to fetal demise. It provides reference data for the diagnosis and prevention of miscarriage. 

Dr. Nguyen Vu Khanh shared “Exploring the genetics of miscarriage reveals that 35% of cases are caused by fetal genetic abnormalities, highlighting the importance of genetic diagnosis in understanding the reasons for pregnancy loss and helping families achieve healthier pregnancies in the future.” 

Thank you to everyone who joined us at the APCMFM Congress and met our team of expert doctors!
#GeneSolutions #GeneticResearch #MaternalFetalHealth #APCMFM2024 #InnovativeHealthcare