Ultra-deep massively parallel sequencing with unique molecular identifier tagging achieves comparable performance to droplet digital PCR for detection and quantification of circulating tumor DNA from lung cancer patients
Key finding:
Identifikasi dan kuantifikasi mutasi yang dapat ditindaklanjuti sangat penting untuk terapi yang diarahkan oleh genotipe, prognosis, dan pemantauan respons obat pada pasien dengan kanker paru non-sel kecil (NSCLC).Publisher:NIH - National Library of Medicine
Publication date:16 December 2019This publication supports for the following genetic testing:
Ultra-Deep Massive Parallel Sequencing of Plasma Cell-Free DNA Enables Large-Scale Profiling of Driver Mutations in Vietnamese Patients With Advanced Non-Small Cell Lung Cancer
Key finding:
Profiling mutasi gen kanker yang spesifik untuk populasi sangat penting untuk pemahaman biologi kanker secara umum serta penetapan pedoman diagnosis dan pengobatan yang optimal untuk populasi tersebut.Publisher:NIH - National Library of Medicine
Publication date:04 August 2020This publication supports for the following genetic testing:
Circulating DNA methylation profile improves the accuracy of serum biomarkers for the detection of nonmetastatic hepatocellular carcinoma
Key finding:
Studi ini memanfaatkan profil metilasi DNA sirkulasi yang spesifik untuk karsinoma hepatoseluler (HCC) untuk meningkatkan akurasi dari tes skrining saat ini bagi pasien HCC di populasi berisiko tinggi.Publisher:NIH - National Library of Medicine
Publication date:14 February 2023This publication supports for the following genetic testing:
National Cancer Society Malaysia and Gene Solutions Forge Partnership to Expand Multi-Cancer Early Detection Awareness and Access
Key finding:
KUALA LUMPUR, Malaysia, July 1, 2024 /PRNewswire/ — National Cancer Society Malaysia (NCSM) and Gene Solutions are pleased to announce the signing of a Memorandum of Understanding (MOU) to collaborate on expanding awareness and enabling access to multi-cancer early detection (MCED) testing for the Malaysian population. This landmark partnership was inked at the inaugural National Cancer Congress Malaysia 2024 and aims to revolutionize cancer detection and improve early diagnosis rates across the nation.Publisher:prnewswire.com
Publication date:01 July 2024
Analytical and clinical validation of a circulating tumor DNA–based assay for multicancer early detection
Authors:
Le Son Tran, Luu Hong Dang Nguyen, Hanh Thi-Hue Nguyen, Duy Sinh Nguyen, Hung Sang Tang, Hoa Giang, Hoai-Nghia Nguyen, Minh-Duy Phan; Medical Genetics Institute; Gene Solutions, Ho Chi Minh City, Viet Nam; Medical Genetics Institute, Ho Chi Minh City, Viet NamEvent:2024 ASCO Annual Meeting
Date:03 June 2024This poster/abstract study shares performance data for:
Analytical validation and clinical utilization of K-4CARE™: a comprehensive genomic profiling assay with personalized MRD detection
Key finding:
Uji K-4CARE™ menyediakan informasi genomik yang komprehensif dan dapat diandalkan yang memenuhi semua uji biomarker berbasis pedoman untuk terapi target dan imunoterapi. Integrasi pelacakan ctDNA membantu klinisi untuk lebih lanjut memantau respons pengobatan dan akhirnya memberikan perawatan yang menyeluruh kepada pasien kanker.Publisher:Frontiers in Molecular Biosciences
Publication date:09 February 2024This publication supports for the following genetic testing:
Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization
Key finding:
Penilaian eLife: Studi ini memberikan wawasan tentang deteksi dini keganasan dengan metode non-invasif dengan mengembangkan kerangka kerja yang menilai metilasi, CNA, dan fitur genomik lainnya. Mereka membangun model yang solid dalam membedakan keganasan dari kontrol sehat, serta kemampuan untuk membedakan tumor berdasarkan asalnya. Studi penting ini akan menunjukkan dampak praktisnya di klinik dan bagi peneliti lain di bidang ini.Publisher:eLife Science
Publication date:11 October 2023This publication supports for the following genetic testing:
Prevalence and genetic spectrum associated with hereditary colorectal cancer syndromes, the need to improve cancer risk awareness, and family cascade testing in Vietnam
Key finding:
Dari semua hasil tes genetik, 3% (49/1632) diidentifikasi dengan mutasi terkait HCCS. Lebih dari 77% dari mereka termasuk dalam sindrom Lynch. PMS2 tampaknya adalah gen dengan frekuensi mutasi tertinggi, sedangkan MLH1 adalah yang terendah. Studi ini memberikan bukti baru mengenai spektrum mutasi HCCS pada populasi Vietnam dan keberhasilan dalam mempromosikan tes kaskade pada anggota keluarga berisiko tinggi melalui dukungan finansial dan teknis.Publisher:Familial cancer
Publication date:30 July 2023This publication supports for the following genetic testing:
Personalized Mutation Tracking in Circulating tumor DNA Detects Recurrence in High-risk Early Breast Cancer
Authors:
Van-Anh Nguyen Hoang, Sao Trung Nguyen, Trieu Vu Nguyen, Thanh Huyen Pham, Nam H Vo, Lan N TuEvent:12th Asia-Pacific Breast Cancer Summit 2024
Date:01 March 2024This poster/abstract study shares performance data for:
K-Track TM: A Streamlined Personalized Assay to Detect Molecular Residual Desease in Solid Tumors
Authors:
Nam H Vo, Van-Anh Nguyen Hoang, Anh-Tuan Nguyen, Hoang-Giang Vu, Lan N TuEvent:ESMO ASIA 2023
Date:02 September 2023This poster/abstract study shares performance data for:
Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization
Authors:
Le Son Tran, Van Thien Chi Nguyen, Hoai-Nghia Nguyen, Hoa Giang, Minh-Duy PhanEvent:ASCO Breakthrough
Date:01 September 2023This poster/abstract study shares performance data for:
Personalized K-Track TM Assay to Detect Actionable Mutations and Minimal Residual Disease in Solid Tumors
Authors:
Lan N Tu, Van-Anh Nguyen HoangEvent:ASCO Breakthrough
Date:01 September 2023This poster/abstract study shares performance data for:
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